Izinja ezi-spayid noma ezingenayo ziyanconywa uma zingasetshenziselwa ukuzalanisa.Kunezinzuzo ezintathu eziyinhloko ze-neutering:

1. Fnoma izinja zesifazane, i-neutering ingavimbela i-estrus, igweme ukukhulelwa okungafunwa, futhi ivimbele izifo zokuzala ezifana nezimila zamabele kanye ne-uterine pyogenesis.Ezinjeni zesilisa, ukuthenwa kungavimbela indlala yendlala yesinye, amasende kanye nezinye izifo zesistimu yokuzala.
2. Ukuvala inzalo kungavimbela ngempumelelo ukulwa, ulaka nokunye ukuziphatha okubi kanye nengozi yokulahleka.
3. I-Neutering inganciphisa inani lezilwane ezilahlekile.Isikhathi esinconywayo sokukhipha i-neutering singaphambi kwe-estrus yokuqala yezinja ezincane nezimaphakathi :izinyanga ezi-5-6 ubudala, izinyanga eziyi-12 ezinjeni ezinkulu.Ingozi ehambisana nokuvala inzalo ngokuyinhloko ukukhuluphala ngokweqile, kodwa ingalawuleka ngokuphakelwa kwesayensi kokudla okuvalwa inzalo.