Ithebhulethi ye-Doxycycline hydrochloride yamakati nezinja

Incazelo emfushane:

Ukutheleleka kwamagciwane amahle, amagciwane angalungile kanye ne-mycoplasma. Izifo zokuphefumula (i-mycoplasma pneumonia, i-chlamydia pneumonia, igatsha le-feline nasal, isifo se-feline calicivirus, i-canine distemper). I-Dermatosis, uhlelo lwe-genitourinary, ukutheleleka kwesisu, njll.


  • Ukusetshenziswa kanye nomthamo:Ngokuphathwa kwangaphakathi: umthamo owodwa, 5 ~ 10mg ngesisindo somzimba esingu-1kg wezinja namakati. Isetshenziswa kanye ngosuku izinsuku ezingama-3-5.
  • Ukucaciswa:200mg/ithebhulethi
  • Imininingwane Yomkhiqizo

    Omaka bomkhiqizo

    Isithako esiyinhloko: I-Doxycycline hydrochloride

    Izakhiwo: Lo mkhiqizo uluhlaza ngokukhanyayo.

    Isenzo se-Pharmacological:

    I-Pharmacodynamics:Lo mkhiqizo iyi-antibiotic ye-tetracycline ebanzi-spectrum enomphumela we-antibacterial obanzi. Amagciwane azwelayo ahlanganisa amagciwane e-Gram-positive afana ne-pneumococcus, i-streptococcus, i-staphylococcus, i-anthrax, i-tetanus, i-corynebacterium namanye amagciwane angenayo i-Gram-negative afana ne-Escherichia coli, i-Pasteurella, i-Salmonella, i-Brucella ne-Haemophilus, i-Klebsiterella kanye ne-meliophilus. Ingase futhi ivimbele i-Rickettsia, i-mycoplasma ne-spirochaeta ngezinga elithile.

    I-Pharmacokinetics:Ukumuncwa okusheshayo, ithonya elincane ngokudla, i-bioavailability ephezulu. Ukugxila kwegazi okuphumelelayo kugcinwa isikhathi eside, ukuvuthwa kwezicubu kunamandla, ukusabalalisa kubanzi, futhi kulula ukungena esitokisini. Ivolumu ebonakalayo yokusabalalisa ezinjeni icishe ibe ngu-1.5L/kg. Izinga eliphezulu lokubopha amaprotheni ezinja 75% kuya ku-86%. Engasebenzi ngokwengxenye yi-chelation emathunjini, i-75% yomthamo wenja ikhishwa ngale ndlela. Ukukhishwa kwezinso cishe ku-25% kuphela, ukukhishwa kwebiliary kungaphansi kuka-5%. Uhhafu wempilo yenja cishe amahora ayi-10 kuya kwayi-12.

    Ukusebenzisana kwezidakamizwa:

    (1) Uma ithathwa ne-sodium bicarbonate, ingakhuphula inani le-pH esiswini futhi inciphise ukumuncwa nokusebenza kwalo mkhiqizo.

    (2) Lo mkhiqizo ungakha ama-complexes ane-divalent and trivalent cations, njll., ngakho-ke lapho ethathwa ne-calcium, i-magnesium, i-aluminium namanye ama-antacids, izidakamizwa ezine-iron noma ubisi nokunye ukudla, ukumuncwa kwazo kuzoncishiswa, okuzoholela ekutheni ukunciphisa ukugcwala kwezidakamizwa egazini.

    (3) Ukusetshenziswa okufanayo nama-diuretics aqinile njenge-furthiamide kungabhebhethekisa ukulimala kwezinso.

    (4) Ingaphazamisa umphumela we-bactericidal we-penicillin ngesikhathi sokuzalanisa kwamagciwane, kufanele igweme ukusetshenziswa okufanayo.

    Izinkomba:

    Ukutheleleka kwamagciwane amahle, amagciwane angalungile kanye ne-mycoplasma. Izifo zokuphefumula (i-mycoplasma pneumonia, i-chlamydia pneumonia, igatsha le-feline nasal, isifo se-feline calicivirus, i-canine distemper). I-Dermatosis, uhlelo lwe-genitourinary, ukutheleleka kwesisu, njll.

    Ukusetshenziswa kanye nomthamo:

    I-Doxycycline. Ngokuphathwa kwangaphakathi: umthamo owodwa, 5 ~ 10mg ngesisindo somzimba esingu-1kg wezinja namakati. Isetshenziswa kanye ngosuku izinsuku ezingama-3-5. Noma njengoba eyalelwe udokotela. Kunconywa ukuthatha ngemva kokudla nokuphuza amanzi amaningi ngemva kokuphathwa ngomlomo.

    Isexwayiso:

    (1) Akunconyelwe izinja namakati ngaphansi kwamasonto amathathu ngaphambi kokubeletha, ukuncelisa, kanye nenyanga engu-1 ubudala.

    (2) Sebenzisa ngokuqapha ezinjeni nasemakati anenkinga enkulu yesibindi nezinso.

    (3) Uma udinga ukuthatha izithako ze-calcium, izithasiselo zensimbi, amavithamini, ama-antacid, i-sodium bicarbonate, njll. ngesikhathi esifanayo, sicela okungenani isikhawu se-2h.

    (4) Akuvunyelwe ukusetshenziswa nama-diuretics kanye ne-penicillin.

    (5) Kuhlanganiswe ne-phenobarbital kanye ne-anticoagulant kuzothinta umsebenzi womunye nomunye.

    Ukusabela okubi:

    (1) Ezinjeni nasemakati, imiphumela emibi evame kakhulu ye-doxycycline yomlomo ukuhlanza, isifo sohudo, nokuncipha kwesifiso sokudla. Ukuze kuncishiswe ukusabela okubi, akukho kuncipha okuphawulekayo kokumuncwa okubonwayo lapho kuthathwa kanye nokudla.

    (2) I-40% yezinja ezilashwayo ibe nokwanda kwama-enzyme ahlobene nokusebenza kwesibindi (i-alanine aminotransferase, i-conglutinase eyisisekelo). Ukubaluleka komtholampilo kokukhuphuka kwama-enzyme ahlobene nokusebenza kwesibindi akucaci.

    (3) I-doxycycline yomlomo ingabangela i-esophageal stenosis emakati, njengamaphilisi omlomo, kufanele iphuzwe okungenani namanzi angu-6ml, hhayi omile.

    (4) Ukwelashwa nge-tetracycline (ikakhulukazi isikhathi eside) kungaholela ekwandeni kwamabhaktheriya angazweli noma isikhunta (ukutheleleka okuphindwe kabili).

    Ithagethi: Okwamakati nezinja kuphela.

    Ukucaciswa: 200mg/ithebhulethi






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